2-Chloro-6-methylaniline
Names
[ CAS No. ]:
87-63-8
[ Name ]:
2-Chloro-6-methylaniline
[Synonym ]:
Benzenamine, 2-chloro-6-methyl-
6-Chloro-o-toluidine
2-Amino-3-chlorotoluene
1-amino-2-methyl-6-chlorobenzene
o-Toluidine,6-chloro
6-chloro-ortho-toluidine
6-Chloro-2-toluidine
6-CHLORO-2-METHYLANILINE
MFCD00007679
Benzenamine,2-chloro-6-methyl
2-methyl-6-chloroaniline
1-Amino-2-chloro-6-methylbenzene
3-Chloro-2-aminotoluene
EINECS 201-759-2
2-Chloro-6-methylaniline
2-Chloro-6-Methylaninile
2-chloro-6-methyl-aniline
2-chloro-6-methylbenzenamine
Rivaroxaban Impurity 50
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
215.0±0.0 °C at 760 mmHg
[ Melting Point ]:
10-12 °C(lit.)
[ Molecular Formula ]:
C7H8ClN
[ Molecular Weight ]:
141.598
[ Flash Point ]:
98.9±0.0 °C
[ Exact Mass ]:
141.034531
[ PSA ]:
26.02000
[ LogP ]:
2.37
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.585
[ Water Solubility ]:
Immiscible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XU5100000
- CHEMICAL NAME :
- o-Toluidine, 6-chloro-
- CAS REGISTRY NUMBER :
- 87-63-8
- BEILSTEIN REFERENCE NO. :
- 0774624
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C7-H8-Cl-N
- MOLECULAR WEIGHT :
- 141.61
- WISWESSER LINE NOTATION :
- ZR BG F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S36-S36/37/39
[ RIDADR ]:
UN 3429 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
XU5100000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2942000000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921430090
[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%