H-Arg-OtBu.2HCl

Names

[ Name ]:
H-Arg-OtBu.2HCl

[Synonym ]:
H-Arg-OtBu.2HCl
2-Methyl-2-propanyl L-argininate dihydrochloride
tert-Butyl L-argininate dihydrochloride
H-Arg-OtBu inverted exclamation mark currency2HCl
L-Arginine t-butyl ester dihydrochloride
L-Arginine, 1,1-dimethylethyl ester, hydrochloride (1:2)

Biological Activity

[Description]:

H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Koh JJ, et al, Beuerman RW. Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections. J Med Chem. 2015 Jan 22;58(2):739-52.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₂₄Cl₂N₄O₂

[ Molecular Weight ]:
303.23

[ Exact Mass ]:
302.127625

[ PSA ]:
114.22000

[ LogP ]:
3.41390

[ Storage condition ]:
Store at 0°C

Safety Information

[ HS Code ]:
2925290090

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%