4′-Hydroxy-2′-methylacetophenone

Names

[ CAS No. ]:
875-59-2

[ Name ]:
4′-Hydroxy-2′-methylacetophenone

[Synonym ]:
1-(4-Hydroxy-2-methylphenyl)ethanone
Ethanone, 1-(4-hydroxy-2-methylphenyl)-
4'-HYDROXY-2'-METHYLACETOPHENONE
EINECS 212-874-2
MFCD00002303

Biological Activity

[Description]:

4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM[1][2].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. GómezGarcía-Carpintero E, et, al. Aroma characterization of red wines from cv. Bobal grape variety grown in La Mancha region. Food Research International. 2011 Jan; 44(1): 61-70.

[2]. Schüürmann G, et, al. Stepwise discrimination between four modes of toxic action of phenols in the Tetrahymena pyriformis assay. Chem Res Toxicol. 2003 Aug;16(8):974-87.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
313.0±0.0 °C at 760 mmHg

[ Melting Point ]:
129-131 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀O₂

[ Molecular Weight ]:
150.174

[ Flash Point ]:
127.9±14.9 °C

[ Exact Mass ]:
150.068085

[ PSA ]:
37.30000

[ LogP ]:
1.88

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.546

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914501900

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%