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Pyruvic acid-13C-2 sodium

Names

[ CAS No. ]:
87976-71-4

[ Name ]:
Pyruvic acid-13C-2 sodium

[Synonym ]:
PYRUVIC-1-13C ACID SODIUM SALT
(13)C1-sodium pyruvate
Pyruvic acid-1-13C sodium salt
PYRUVIC ACID, SODIUM SALT (1-13C)
Sodium pyruvate-1-13C
sodium [1-(13)C]pyruvate
MFCD00084079
2-oxo-[1-13C]propanoic acid sodium salt
sodium (13)C-1-pyruvate
Propanoic-1-13Cacid,2-oxo-,sodium salt (9CI)
(1-13C)-sodium pyruvate
(1-13C)-pyruvate sodium salt
Sodium Pyruvate (1-13C, 99%)

Biological Activity

[Description]:

Pyruvic acid-13C-2 (sodium) is the 13C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Kładna A, et al. Reactivity of pyruvic acid and its derivatives towards reactive oxygen species. Luminescence. 2015 Nov;30(7):1153-8.  

Chemical & Physical Properties

[ Melting Point ]:
>300ºC(lit.)

[ Molecular Formula ]:
C3H3NaO3

[ Molecular Weight ]:
111.03700

[ Exact Mass ]:
111.00100

[ PSA ]:
57.20000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds