fluxofenim

Names

[ Name ]:
fluxofenim

[Synonym ]:
(1Ξ)-1-(4-chlorophenyl)-N-(1,3-dioxolan-2-ylmethoxy)-2,2,2-trifluoroethan-1-imine
(4-chlorobenzoylmethylene)triphenylphosphorane
1-(4-Chlorophenyl)-2-(3-pyridinyl)ethanone
1-(4-chlorophenyl)-2-(triphenylphosphanylidene)ethanone
Ph3P=COC6H4Cl
1-(4-chlorophenyl)-2-(triphenylphosphosphanylidene)ethanone
1-(4-chlorophenyl)-2-(triphenylphosphoranylidene)ethanone
1-(4-chlorophenyl)-2,2,2-trifluoro-1-ethanone O-(1,3-dioxolan-2-ylmethyl)oxime
4’-chloro-2,2,2-trifluoroacetophenone (EZ)-O-1,3-dioxolan-2-ylmethyloxime
1-(4-chloro-phenyl)-2-pyridin-3-yl-ethanone
(p-Chlorobenzoylmethylene)triphenylphosphorane
[(p-chlorobenzoyl)methylene]triphenylphosphoran
1-(4-chlorophenyl)-1-(1,3-dioxolan-2-ylmethoximino)-2,2,2-trifluoroethane
(pyrid-3-ylmethyl)-(4-chlorophenyl)-ketone
(1Z)-1-(4-Chlorophenyl)-N-(1,3-dioxolan-2-ylmethoxy)-2,2,2-triflu oroethanimine
1-(4-chlorophenyl)-2,2,2-trifluoroethanone O-(1,3-dioxolan-2-ylmethyl)oxime
4'-chloro-2-(3-pyridyl)-acetophenone
1-(4-CHLOROPHENYL)-2-(3-PYRIDYL)ETHANONE

Chemical & Physical Properties

[ Density]:
1.43g/cm3

[ Boiling Point ]:
309.5ºC at 760 mmHg

[ Melting Point ]:
25°C

[ Molecular Formula ]:
C₁₂H₁₁ClF₃NO₃

[ Molecular Weight ]:
309.66900

[ Flash Point ]:
141ºC

[ Exact Mass ]:
309.03800

[ PSA ]:
40.05000

[ LogP ]:
2.99590

[ Index of Refraction ]:
1.509

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM5638200

CHEMICAL NAME :: Ethanone, 1-(4-chlorophenyl)-2,2,2-trifluoro-, O-(1,3-dioxolan-2-ylmethyl)oxime

CAS REGISTRY NUMBER :: 88485-37-4

LAST UPDATED :: 199806

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C12-H11-Cl-F3-N-O3

MOLECULAR WEIGHT :: 309.69

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 669 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C79,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1210 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1190-1081 FLWP

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1540 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,430,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1544 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C79,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1480 mg/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Gastrointestinal - other changes Musculoskeletal - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535321 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10500 mg/kg/4W-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1190-1081 FLWP

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H315-H330-H400

[ Precautionary Statements ]:
P260-P273-P280-P284-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
R21/22

[ Safety Phrases ]:
36/37/39-60-61

[ RIDADR ]:
UN3082 9/PG 3

[ RTECS ]:
KM5638200

Articles

Festuca arundinacea, glutathione S-transferase and herbicide safeners: a preliminary case study to reduce herbicidal pollution.

J. Environ. Sci. Health B 44(8) , 805-9, (2009)

The expression of glutathione S-transferase (GST) activity in Festuca arundinacea was investigated in response to the following herbicide safeners: benoxacor, cloquintocet-mexyl, fenchlorazol-ethyl, f...

Induction of glutathione S-transferases in Arabidopsis by herbicide safeners.

Plant Physiol. 130(3) , 1497-505, (2002)

Herbicide safeners increase herbicide tolerance in cereals but not in dicotyledenous crops. The reason(s) for this difference in safening is unknown. However, safener-induced protection in cereals is ...

Organ-specific expression of glutathione S-transferases and the efficacy of herbicide safeners in Arabidopsis.

Plant Physiol. 140(1) , 167-75, (2006)

The functions of plant glutathione S-transferases (GSTs) under normal growth conditions are poorly understood, but their activity as detoxification enzymes has been harnessed in agriculture for select...