2,4-Dichlorobenzoyl chloride

Names

[ CAS No. ]:
89-75-8

[ Name ]:
2,4-Dichlorobenzoyl chloride

[Synonym ]:
EINECS 201-936-4
2,4-dichloro-benzoyl chloride
2,4-dichlorobenzoic acid chloride
2,4-Dichlorobenzoyl chloride
Benzoyl chloride,2,4-dichloro
MFCD00009817
2,4,5-TRIMETHYLTHIOPHENOL
Benzoyl chloride, 2,4-dichloro-
GVR BG DG
o,p-dichlorobenzoyl chloride

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
251.8±20.0 °C at 760 mmHg

[ Melting Point ]:
28 °C(lit.)

[ Molecular Formula ]:
C₇H₃Cl₃O

[ Molecular Weight ]:
209.457

[ Flash Point ]:
103.4±22.3 °C

[ Exact Mass ]:
207.924942

[ PSA ]:
17.07000

[ LogP ]:
3.16

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.577

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
DM6636766

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29163900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators.

Bioorg. Med. Chem. Lett. 12(24) , 3565-7, (2002)

A series of 5-substituted 2-benzoylaminobenzoic acids has been synthesized and assayed for PPARalpha/gamma activity. Both dual activators and selective PPARgamma agonists have been identified. This cl...

NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A.

J. Bacteriol. 178(9) , 2656-61, (1996)

Corynebacterium sepedonicum KZ-4, described earlier as a strain capable of growth on 2,4-dichlorobenzoate (G.M. Zaitsev and Y.N. Karasevich, Mikrobiologiya 54:356-369, 1985), is known to metabolize th...

Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides.

Bioorg. Med. Chem. Lett. 16(23) , 5968-72, (2006)

This Letter describes the synthesis and SAR, developed through an iterative analog library approach, of potent and selective non-sarcosine-derived GlyT1 inhibitors.