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Thymopentin acetate

Names

[ CAS No. ]:
89318-88-7

[ Name ]:
Thymopentin acetate

[Synonym ]:
UNII-1938Y8P51M
Thymopentin monoacetate

Biological Activity

[Description]:

Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs)[1][2].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Inflammation/Immunology

[In Vitro]

Thymopentin acetate enhances the generation of T-cell lineage derived from hESCs in vitro [1].

[References]

[1]. Zhu MX, et al. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells in vitro. Exp Cell Res. 2015 Feb 15;331(2):387-98.

[2]. Lin S, et al. Novel strategy for immunomodulation: Dissolving microneedle array encapsulating thymopentin fabricated by modified two-step molding technology. Eur J Pharm Biopharm. 2018 Jan;122:104-112.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H53N9O11

[ Molecular Weight ]:
739.81700

[ Exact Mass ]:
739.38600

[ PSA ]:
376.43000

[ LogP ]:
3.85240

Related Compounds