Phosphoglucomutase

Names

[ Name ]:
Phosphoglucomutase

[Synonym ]:
2-[(3-Aminopropanoyl)amino]-3-(1H-imidazol-4-yl)propanoic acid
Histidine, β-alanyl-
b-Alanylhistidine
β-Alanylhistidine
carnosine
N-(3-Aminopropanoyl)histidine

Biological Activity

[Description]:

Phosphoglucomutase is often used in biochemical studies. Phosphoglucomutase is an enzyme that can transfer the phosphate group on the α-D-glucose monomer forward from the 1-position to the 6-position or reversely transfer from the 6-position to the 1-position, and promote the glucose-1-phosphate and glucose-6-phosphate Transform each other. Phosphoglucomutase is a key enzyme in glycolysis and gluconeogenesis, and plays an important role in the metabolism of proteins, lipids and nucleic acids[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Bi-Ying Pan, et al. Role of phosphoglucomutase in regulating trehalose metabolism in Nilaparvata lugens. 3 Biotech. 2020 Feb;10(2):61.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
656.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₄N₄O₃

[ Molecular Weight ]:
226.232

[ Flash Point ]:
350.7±31.5 °C

[ Exact Mass ]:
226.106583

[ LogP ]:
-2.17

[ Appearance of Characters ]:
ammonium sulfate suspension

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.591

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
35079090

Articles

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

Sci. Signal. 2 , ra46, (2009)

Protein phosphorylation events during T cell receptor (TCR) signaling control the formation of complexes among proteins proximal to the TCR, the activation of kinase cascades, and the activation of tr...

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

Cell 127(3) , 635-648, (2006)

Cell signaling mechanisms often transmit information via posttranslational protein modifications, most importantly reversible protein phosphorylation. Here we develop and apply a general mass spectrom...