ec 4.1.3.3
Names
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.000 g/cm3
[ Molecular Formula ]:
C23H42O5
[ Molecular Weight ]:
398.583
[ Appearance of Characters ]:
powder | slightly yellow
[ Storage condition ]:
−20°C
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
23-24/25-60-37-26-22
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Adv. Carbohydr. Chem. Biochem. 40 , 131, (1982)
Structural basis for substrate specificity and mechanism of N-acetyl-D-neuraminic acid lyase from Pasteurella multocida.
Biochemistry 52(47) , 8570-9, (2013)
N-Acetylneuraminate lyases (NALs) or sialic acid aldolases catalyze the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac, the most common form of sialic acid) to form pyruvate and N-acetyl...
Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with γ-thialysine by using a chemical mutagenesis strategy.ChemBioChem. 14(4) , 474-81, (2013)
Chemical modification has been used to introduce the unnatural amino acid γ-thialysine in place of the catalytically important Lys165 in the enzyme N-acetylneuraminic acid lyase (NAL). The Staphylococ...