3-Hydroxybutyrate dehydrogenase

Names

[ Name ]:
3-Hydroxybutyrate dehydrogenase

[Synonym ]:
beta-hydroxybutyrate dehydrogenase
ec 1.1.1.30
beta-hydroxybutyrate dehydrogenase type v
ec 1.1.1.30 type v
ec: 1.1.1.30
MFCD00130633
3-hbdh
1H-Indole-3-propanamide, N-[3-[[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]methylamino]propyl]-
N-{3-[{3-[(6-Chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl}(methyl)amino]propyl}-3-(1H-indol-3-yl)propanamide
N-{3-[{3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}(methyl)amino]propyl}-3-(1H-indol-3-yl)propanamide
d-3-hydroxybutyrate: nad oxidoreductase
d-3-hydroxybutyrate dehydrogenase

Biological Activity

[Description]:

3-Hydroxybutyrate dehydrogenase (3-HBDH) is a mitochondrial enzyme, is often used in biochemical studies. 3-hydroxybutyrate dehydrogenase is involved in the synthesis and degradation of ketone bodies and butanoate metabolism. 3-Hydroxybutyrate dehydrogenase catalyzes (R)-3-hydroxybutanoate converts into acetoacetate[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Watson HR, Lindsay DB. 3-hydroxybutyrate dehydrogenase in tissues from normal and ketonaemic sheep. Biochem J. 1972 Jun;128(1):53-7.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
806.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₁H₃₈ClN₅O

[ Molecular Weight ]:
532.119

[ Flash Point ]:
441.7±34.3 °C

[ Exact Mass ]:
531.276489

[ LogP ]:
5.89

[ Appearance of Characters ]:
lyophilized powder

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.663

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
35079090

Articles

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet. 36 , 40-5, (2004)

As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clone...

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res. 14 , 2121-7, (2004)

The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for...