CeMMEC2
Names
[ CAS No. ]:
902955-25-3
[ Name ]:
CeMMEC2
[Synonym ]:
1,2,4-Triazolo[4,3-b]pyridazin-6-amine, N-[2-(1-cyclohexen-1-yl)ethyl]-3-methyl-
N-[2-(1-Cyclohexen-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine
Biological Activity
[Description]:
CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.
[References]
References 1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10. 2. Blank, J. et al. WPO patent WO/2014/191894 (2014). View Related Products by Target Bromodomain
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Molecular Formula ]:
C14H19N5
[ Molecular Weight ]:
257.334
[ Exact Mass ]:
257.164032
[ LogP ]:
2.41
[ Index of Refraction ]:
1.673