MALTOSE PHOSPHORYLASE

Names

[ Name ]:
MALTOSE PHOSPHORYLASE

[Synonym ]:
4-Acetoxy-1,7,10-trihydroxy-13-{[2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
MFCD03457426
Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl- 5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester

Biological Activity

[Description]:

Maltose phosphorylase is a dimerase which catalyzes the transformation of maltose and inorganic phosphate into β-D-glucose-1-phosphate and glucose. Maltose phosphorylases have been classified in family 65 of the glycoside hydrolases[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Egloff MP, et al. Crystal structure of maltose phosphorylase from Lactobacillus brevis: unexpected evolutionary relationship with glucoamylases. Structure. 2001 Aug;9(8):689-97.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
900.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₃H₅₃NO₁₄

[ Molecular Weight ]:
807.879

[ Flash Point ]:
498.4±34.3 °C

[ Exact Mass ]:
807.346619

[ LogP ]:
6.55

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.618

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Enzymatic synthesis of alpha-anomer-selective D-glucosides using maltose phosphorylase.

Biosci. Biotechnol. Biochem. 71 , 1598-1600, (2007)

A maltose phosphorylase (EC 2.4.1.8; MPase) showed novel acceptor specificity and transferred the glucosyl moiety of maltose not only to sugars but also to various acceptors having alcoholic OH groups...

Rational engineering of Lactobacillus acidophilus NCFM maltose phosphorylase into either trehalose or kojibiose dual specificity phosphorylase.

Protein Eng. Des. Sel. 23(10) , 781-7, (2010)

Lactobacillus acidophilus NCFM maltose phosphorylase (LaMP) of the (alpha/alpha)(6)-barrel glycoside hydrolase family 65 (GH65) catalyses both phosphorolysis of maltose and formation of maltose by rev...

Development of a conductometric phosphate biosensor based on tri-layer maltose phosphorylase composite films.

Anal. Chim. Acta 615(1) , 73-9, (2008)

A conductometric biosensor for phosphate detection was developed using maltose phosphorylase (MP) from recombinant Escherichia coli immobilized on a planar interdigitated electrode by cross-linking wi...