Alcohol dehydrogenase

Names

[ Name ]:
Alcohol dehydrogenase

[Synonym ]:
Benzamide, N-(3-methoxyphenyl)-3-[(1-oxopropyl)amino]-
N-(3-Methoxyphenyl)-3-(propionylamino)benzamide
MFCD00081305

Biological Activity

[Description]:

Alcohol dehydrogenase is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Crabb DW, et al. Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology. Proc Nutr Soc. 2004 Feb;63(1):49-63.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
448.1±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₈N₂O₃

[ Molecular Weight ]:
298.336

[ Flash Point ]:
224.8±24.6 °C

[ Exact Mass ]:
298.131744

[ LogP ]:
2.53

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.633

[ Storage condition ]:
-20C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
SZ5999500

Articles

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet. 36 , 40-5, (2004)

As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clone...

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res. 14 , 2121-7, (2004)

The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for...