Bleomycin B2
Names
[ CAS No. ]:
9060-10-0
[ Name ]:
Bleomycin B2
[Synonym ]:
N1-[4-[[Amino(imino)methyl]amino]butyl]bleomycinamide
Zhengguanmycin B2
Dehydrophleomycin D1
Phleomycin D2
BLEMOYCIN BZ
Epi-Bleomycin
Chemical & Physical Properties
[ Density]:
1.79g/cm3
[ Molecular Formula ]:
C55H84N20O21S2
[ Molecular Weight ]:
1425.51000
[ Exact Mass ]:
1424.56000
[ PSA ]:
745.45000
[ Index of Refraction ]:
1.768
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EC5991200
- CHEMICAL NAME :
- Bleomycinamide, N(sup 1)-(4-((aminoiminomethyl)amino)butyl)-
- CAS REGISTRY NUMBER :
- 9060-10-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C55-H84-N20-O21-S2
- MOLECULAR WEIGHT :
- 1425.71
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intratracheal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - fibrosis (interstitial)
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 10700 pmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,4173,1980