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Bleomycin B2

Names

[ CAS No. ]:
9060-10-0

[ Name ]:
Bleomycin B2

[Synonym ]:
N1-[4-[[Amino(imino)methyl]amino]butyl]bleomycinamide
Zhengguanmycin B2
Dehydrophleomycin D1
Phleomycin D2
BLEMOYCIN BZ
Epi-Bleomycin

Chemical & Physical Properties

[ Density]:
1.79g/cm3

[ Molecular Formula ]:
C55H84N20O21S2

[ Molecular Weight ]:
1425.51000

[ Exact Mass ]:
1424.56000

[ PSA ]:
745.45000

[ Index of Refraction ]:
1.768

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EC5991200
CHEMICAL NAME :
Bleomycinamide, N(sup 1)-(4-((aminoiminomethyl)amino)butyl)-
CAS REGISTRY NUMBER :
9060-10-0
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C55-H84-N20-O21-S2
MOLECULAR WEIGHT :
1425.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intratracheal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - fibrosis (interstitial)

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
10700 pmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,4173,1980

Related Compounds