Oxodipine
Names
[ CAS No. ]:
90729-41-2
[ Name ]:
Oxodipine
[Synonym ]:
Oxodipinum
IQB-837-V
Oxodipino [Spanish]
Oxodipinum [Latin]
Oxodipine [INN]
3,5-Pyridinedicarboxylic acid,1,4-dihydro-4-(1,3-benzodioxol-4-yl)-2,6-dimethyl-,ethyl methyl ester
Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(2,3-(methylenedioxy)phenyl)-3,5-pyridinedicarboxylate
OXODIPINE
Oxodipino
Chemical & Physical Properties
[ Density]:
1.247g/cm3
[ Boiling Point ]:
470ºC at 760 mmHg
[ Molecular Formula ]:
C19H21NO6
[ Molecular Weight ]:
359.37300
[ Flash Point ]:
238ºC
[ Exact Mass ]:
359.13700
[ PSA ]:
83.09000
[ LogP ]:
2.71500
[ Index of Refraction ]:
1.552
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US7968500
- CHEMICAL NAME :
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(1,3-benzodioxol-4-yl)-2,6-dimethyl-, ethyl methyl ester
- CAS REGISTRY NUMBER :
- 90729-41-2
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C19-H21-N-O6
- MOLECULAR WEIGHT :
- 359.41
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,633,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 54(2),40,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 2160 mg/kg/13W-I
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section Endocrine - other changes Endocrine - changes in adrenal weight
- REFERENCE :
- TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 20,549,1992