thenyldiamine
Names
[ CAS No. ]:
91-79-2
[ Name ]:
thenyldiamine
[Synonym ]:
Tenildiamina [INN-Spanish]
Tenfidil
Thenyldiaminum [INN-Latin]
Thefanil
Thenyldiamine
Thenyldiamine (pharmaceutical)
N,N-dimethyl-N'-[2]pyridyl-N'-[3]thienylmethyl-ethylenediamine
Thenfadil
Dethylandiamine
Thenyldiamin
N,N-Dimethyl-N'-[2]pyridyl-N'-[3]thienylmethyl-aethylendiamin
Chemical & Physical Properties
[ Density]:
1.1388 (rough estimate)
[ Boiling Point ]:
169-172ºC at 1.0 MM HG
[ Molecular Formula ]:
C14H19N3S
[ Molecular Weight ]:
261.38600
[ Exact Mass ]:
261.13000
[ PSA ]:
47.61000
[ LogP ]:
2.71130
[ Index of Refraction ]:
nD20 1.5915
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UT1575000
- CHEMICAL NAME :
- Pyridine, 2-((2-(dimethylamino)ethyl)-3-thenylamino)-
- CAS REGISTRY NUMBER :
- 91-79-2
- BEILSTEIN REFERENCE NO. :
- 0221267
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H19-N3-S
- MOLECULAR WEIGHT :
- 261.42
- WISWESSER LINE NOTATION :
- T6NJ BN2N1&1&1- CT5SJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 77 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 30 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981