1-O-HEXADECYL-2-N-METHYLCARBAMYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Names

[ Name ]:
1-O-HEXADECYL-2-N-METHYLCARBAMYL-SN-GLYCERO-3-PHOSPHOCHOLINE

[Synonym ]:
MFCD00065891
Ethanaminium, 2-[[[(2R)-3-(hexadecyloxy)-2-[[(methylamino)carbonyl]oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
Methylcarbamol
mc-PAF
mcPlatelet activating factor
(2R)-3-(Hexadecyloxy)-2-[(methylcarbamoyl)oxy]propyl 2-(trimethylammonio)ethyl phosphate
cPAF

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₅₅N₂O₇P

[ Molecular Weight ]:
538.698

[ Exact Mass ]:
538.374695

[ PSA ]:
115.96000

[ LogP ]:
3.92

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Staphylococcal lipoteichoic acid inhibits delayed-type hypersensitivity reactions via the platelet-activating factor receptor.

J. Clin. Invest. 115(10) , 2855-61, (2005)

Staphylococcus aureus infections are known triggers for skin inflammation and can modulate immune responses. The present studies used model systems consisting of platelet-activating factor receptor-po...

Platelet-activating factor biosynthesis induced by various stimuli in human HaCaT keratinocytes.

J. Invest. Dermatol. 107(1) , 88-94, (1996)

Platelet-activating factor (PAF) is a potent inflammatory mediator that is thought to play a role in cutaneous inflammation. These studies used mass spectrometry to examine the molecular species of PA...

The secreted protease factor CPAF is responsible for degrading pro-apoptotic BH3-only proteins in Chlamydia trachomatis-infected cells.

J. Biol. Chem. 281(42) , 31495-501, (2006)

Chlamydia trachomatis has evolved a profound anti-apoptotic activity that may aid in chlamydial evasion of host defense. The C. trachomatis anti-apoptotic activity has been correlated with blockade of...