8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine

Names

[ Name ]:
8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine

[Synonym ]:
8-chloro-1-phenyl[1,2,4]triazolo[4,3-a]quinoxalin-4-amine
4-amino-8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxaline

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Molecular Formula ]:
C₁₅H₁₀ClN₅

[ Molecular Weight ]:
295.72600

[ Exact Mass ]:
295.06200

[ PSA ]:
69.10000

[ LogP ]:
3.76130

[ Index of Refraction ]:
1.792

MSDS

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Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

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Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.

Eur. J. Pharmacol. 380(2-3) , 197-202, (1999)

We have examined the potency of several adenosine receptor antagonists at adenosine A1 and A2A receptors using quantitative autoradiography and have compared the results with those of previous studies...

Propentofylline inhibits polymorphonuclear leukocyte recruitment in vivo by a mechanism involving adenosine A2A receptors.

Eur. J. Pharmacol. 313(3) , 237-42, (1996)

Propentofylline is an atypical xanthine derivative that blocks adenosine uptake and has been shown to protect against ischemia-induced cerebral damage. We have studied the effect of propentofylline on...

Adenosine receptor-mediated modulation of acetylcholine release from rat striatal synaptosomes.

Br. J. Pharmacol. 110(3) , 949-54, (1993)

1. The effects of A1 and A2a adenosine receptor agonists on the veratridine-evoked release of [3H]-acetylcholine ([3H]-ACh) from rat striatal synaptosomes was investigated by use of the A1-selective a...