phenyltoloxamine
Names
[ CAS No. ]:
92-12-6
[ Name ]:
phenyltoloxamine
[Synonym ]:
Feniltolossamina [DCIT]
Phenyltoloxamine
Phenoxadrine
Antin
[2-(2-benzyl-phenoxy)-ethyl]-dimethyl-amine
Histionex
2-Dimethylamino-1-(2-benzyl-phenoxy)-aethan
Bistrimin
Phenoxadrin
UNII-K65LB6598J
Phenyl-toloxamin
Phentoloxamine
Bristamin
[2-(2-Benzyl-phenoxy)-aethyl]-dimethyl-amin
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Sigma 1 Receptor:160 nM (Ki)
[In Vitro]
Chemical & Physical Properties
[ Density]:
1.022g/cm3
[ Boiling Point ]:
359.2ºC at 760 mmHg
[ Molecular Formula ]:
C17H21NO
[ Molecular Weight ]:
255.35500
[ Flash Point ]:
106ºC
[ Exact Mass ]:
255.16200
[ PSA ]:
12.47000
[ LogP ]:
3.21780
[ Index of Refraction ]:
1.552
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KH2376000
- CHEMICAL NAME :
- Ethanamine, N,N-dimethyl-2-(2-(phenylmethyl)phenoxy)-
- CAS REGISTRY NUMBER :
- 92-12-6
- BEILSTEIN REFERENCE NO. :
- 1986598
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C17-H21-N-O
- MOLECULAR WEIGHT :
- 255.39
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1127 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 246 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83250 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 9 No. of Employees: 934 (estimated) No. of Female Employees: 506 (estimated)