4-Phenylmorpholine
Names
[ CAS No. ]:
92-53-5
[ Name ]:
4-Phenylmorpholine
[Synonym ]:
MFCD00006166
Phenyl morpholine
4-Phenylmorpholine
Morpholinobenzene
EINECS 202-164-0
4-Phenyl-morpholine
(4-morpholinyl)benzene
Morpholine, 4-phenyl-
MORPHOLINE,4-PHENYL
N-phenyl-morpholine
4-PHENYL MORPHOLINE
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
264.8±0.0 °C at 760 mmHg
[ Melting Point ]:
51-54 °C(lit.)
[ Molecular Formula ]:
C10H13NO
[ Molecular Weight ]:
163.216
[ Flash Point ]:
80.6±27.7 °C
[ Exact Mass ]:
163.099716
[ PSA ]:
12.47000
[ LogP ]:
1.36
[ Vapour density ]:
5.63 (vs air)
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.542
[ Water Solubility ]:
3.46 g/L
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QE8575000
- CHEMICAL NAME :
- Morpholine, 4-phenyl-
- CAS REGISTRY NUMBER :
- 92-53-5
- BEILSTEIN REFERENCE NO. :
- 0132159
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H13-N-O
- MOLECULAR WEIGHT :
- 163.24
- WISWESSER LINE NOTATION :
- T6N DOTJ AR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/13/1972 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 930 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 360 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/13/1972
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H311
[ Precautionary Statements ]:
P280-P312
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R22;R24
[ Safety Phrases ]:
S36/37-S45-S36/37/39-S28A
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
QE8575000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
29349990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Chem. Soc. , 3032-39, (1957)
Different levels of protective alkaloids in grasses with stroma-forming and seed-transmitted Epichloë/Neotyphodium endophytes. Leuchtmann A, et al.
J. Chem. Ecol. 26(4) , 1025-36, (2000)