Levocarnitine impurity A

Names

[ CAS No. ]:
927-89-9

[ Name ]:
Levocarnitine impurity A

[Synonym ]:
4-(trimethylammonio)but-2-enoate
Crotonsaeure-betain
(E)-4-(trimethylazaniumyl)but-2-enoate
(2E)-4-(Trimethylammonio)-2-butenoate
Crotonbetain
2-Propen-1-aminium, 3-carboxy-N,N,N-trimethyl-, inner salt, (2E)-
Crotonic acid betaine
Apocarnitin
Croton betaine
Crotonobetaine

Chemical & Physical Properties

[ Molecular Formula ]:
C₇H₁₃NO₂

[ Molecular Weight ]:
143.184

[ Exact Mass ]:
143.094635

[ PSA ]:
40.13000

[ LogP ]:
-3.17

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BP2018000

CHEMICAL NAME :: Ammonium, (3-carboxyallyl)trimethyl-, hydroxide, inner salt

CAS REGISTRY NUMBER :: 927-89-9

LAST UPDATED :: 198912

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H13-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 3,28,1959

Articles

Effect of salt stress on crotonobetaine and D(+)-carnitine biotransformation into L(-)-carnitine by resting cells of Escherichia coli.

J. Basic Microbiol. 43(4) , 259-68, (2003)

The biotransformation of crotonobetaine and D(+)-carnitine into L(-)-carnitine is affected by salt stress in the resting cells of E. coli O44 K74 and the transformed E. coli K38 pT7-5KE32. A yield of ...

Biotransformation of crotonobetaine to L(-)-carnitine in Proteus sp.

Arch. Microbiol. 175(5) , 353-9, (2001)

Two proteins, component I (CI) and component II (CII), catalyze the biotransformation of crotonobetaine to L(-)-carnitine in Proteus sp. CI was purified to electrophoretic homogeneity from cell-free e...

Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.

Mol. Microbiol. 13(5) , 775-86, (1994)

The sequence encompassing the cai genes of Escherichia coli, which encode the carnitine pathway, has been determined. Apart from the already identified caiB gene coding for the carnitine dehydratase, ...