N-Benzyl-2-bromo-propionanilide

Names

[ Name ]:
N-Benzyl-2-bromo-propionanilide

[Synonym ]:
N-benzyl-N-phenyl-2-bromopropanamide
N-Benzyl-2-bromo-propionanilide
2-Bromo-N-phenyl-N-(phenylmethyl)propanamide
2-Brom-propionsaeure-(N-benzyl-anilid)
N-Benzyl-2-bromo-N-phenylpropionamide
(+-)-2-Brom-propionsaeure-(N-phenyl-benzylamid)
2-bromo-propionic acid-(N-benzyl-anilide)

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₆BrNO

[ Molecular Weight ]:
318.20800

[ Exact Mass ]:
317.04200

[ PSA ]:
20.31000

[ LogP ]:
4.00320

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
UN 2923 6.1(8) / PGII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Asymmetric nickel-catalyzed Negishi cross-couplings of secondary alpha-bromo amides with organozinc reagents.

J. Am. Chem. Soc. 127 , 4594, (2005)

A Ni/Pybox catalyst achieves the asymmetric cross-coupling of secondary alpha-bromo amides with organozinc reagents. The process tolerates a variety of functional groups and affords the desired produc...