Cyclohexanecarboxylic acid-d11

Names

[ Name ]:
Cyclohexanecarboxylic acid-d11

[Synonym ]:
1,4-[2H10]xylene
(2H10)-p-Xylene
d10-p-xylene
D11 cyclohexanecarboxylic acid
1,4-Di(methyl-d3)benzene-d4
perdeuterocyclohexanecarboxylic acid
Benzene-1,2,4,5-d4-,3,6-di(methyl-d3)
1,4-bis[(2h3)methyl](2h4)benzene
1,4-Dimethylbenzene-d10
p-Xylene-d10
[1,2,2,3,3,4,4,5,5,6,6-2H11]cyclohexanecarboxylic acid

Biological Activity

[Description]:

Cyclohexanecarboxylic acid-d11 is the deuterium labeled Cyclohexanecarboxylic acid[1]. Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action[2].

[Related Catalog]:

Research Areas >> Neurological Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Liu MJ, et al. Pharmacokinetics and pharmacodynamics of valproate analogues in rats. IV. Anticonvulsant action and neurotoxicity of octanoic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid. Epilepsia. 1994 Jan-Feb;35(1):234-43.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇HD₁₁O₂

[ Molecular Weight ]:
139.23700

[ Exact Mass ]:
139.15300

[ PSA ]:
37.30000

[ LogP ]:
1.65130

[ Storage condition ]:
2-8°C

Cyclohexanecarboxylic acid-d11

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds