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AZD 2066

Names

[ CAS No. ]:
934282-55-0

[ Name ]:
AZD 2066

[Synonym ]:
unii-mq908y1zb2
azd2066

Biological Activity

[Description]:

AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR

Research Areas >> Neurological Disease

[References]

[1]. Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350(2):212-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆ClN₅O₂

[ Molecular Weight ]:
381.81600

[ Exact Mass ]:
381.09900

[ PSA ]:
78.86000

[ LogP ]:
4.32550

[ Storage condition ]:
2-8°C

Related Compounds