2,4'-dichloroacetophenone
Names
[ CAS No. ]:
937-20-2
[ Name ]:
2,4'-dichloroacetophenone
[Synonym ]:
2,4'-dichloroacetophenone
Ethanone, 2-chloro-1-(4-chlorophenyl)-
MFCD00018926
2-Chloro-1-(4-chlorophenyl)ethanone
EINECS 213-323-9
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
270.0±0.0 °C at 760 mmHg
[ Melting Point ]:
100-102 °C(lit.)
[ Molecular Formula ]:
C8H6Cl2O
[ Molecular Weight ]:
189.039
[ Flash Point ]:
119.1±21.0 °C
[ Exact Mass ]:
187.979568
[ PSA ]:
17.07000
[ LogP ]:
2.53
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.551
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
UN 3335
[ WGK Germany ]:
3
[ HS Code ]:
2914700090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
Org. Lett. 9(2) , 255-257, (2007)
Asymmetric hydrogenation of various alpha-chloro aromatic ketones with Ru(OTf)(TsDPEN)(eta6-arene) (TsDPEN = N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine) produces the chiral chlorohydrins in up ...
Purification and characterization of a yeast carbonyl reductase for synthesis of optically active (R)-styrene oxide derivatives.Biosci. Biotechnol. Biochem. 69(1) , 79-86, (2005)
Optically active styrene oxide derivatives are versatile chiral building blocks. Stereoselective reduction of phenacyl halide to chiral 2-halo-1-phenylethanol is the key reaction of the most economica...
Direct Investigation of Covalently Bound Chlorine in Organic Compounds by Solid-State 35Cl NMR Spectroscopy and Exact Spectral Line-Shape Simulations. Perras FA and Bryce DL.Angew. Chem. Weinheim Bergstr. Ger. 124(11) , 4303-4306, (2012)