Aurora B inhibitor 1

Names

[ Name ]:
Aurora B inhibitor 1

Biological Activity

[Description]:

Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.

[Related Catalog]:

Research Areas >> Cancer

[Target]

Aurora B:0.01 μM (Ki)

[In Vitro]

Aurora B inhibitor 1 also inhibits JAK3 and JAK2 with Kis of <0.25 μM and <0.10 μM, respectively[1].

[References]

[1]. FRAYSSE, Damien, et al. AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS. WO2007059299A1.

[Related Small Molecules]

Alisertib (MLN8237) | Tozasertib | AT9283 | Barasertib (AZD1152-HQPA) | danusertib | Hesperadin | Reversine | MLN8054 | GSK1070916 | AMG-900 | KW-2449 | TAK-632 | TAK-901 | MK-5108(VX-689) | pf-03814735

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₆ClF₂N₇O₂

[ Molecular Weight ]:
529.97

Aurora B inhibitor 1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds