(S)-4-Fluorophenylglycine

Names

[ Name ]:
(S)-4-Fluorophenylglycine

[Synonym ]:
(2R)-2-amino-2-(4-fluorophenyl)acetic acid
Benzeneacetic acid, α-amino-4-fluoro-, (αR)-
(2S)-Amino(4-fluorophenyl)acetic acid
Benzeneacetic acid, α-amino-4-fluoro-, (αS)-
(S)-4-Fluorophenylglycine
QVYZR DF &&S Form
MFCD00042727
(2R)-amino(4-fluorophenyl)ethanoic acid
(R)-4-FLUOROPHENYLGLYCINE
(2S)-Amino(4-fluorophenyl)ethanoic acid
(2R)-Amino(4-fluorophenyl)acetic acid
EINECS 300-363-8

Biological Activity

[Description]:

(R)-2-Amino-2-(4-fluorophenyl)acetic acid is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
289.9±30.0 °C at 760 mmHg

[ Melting Point ]:
≥300 °C

[ Molecular Formula ]:
C₈H₈FNO₂

[ Molecular Weight ]:
169.153

[ Flash Point ]:
129.1±24.6 °C

[ Exact Mass ]:
169.053909

[ PSA ]:
63.32000

[ LogP ]:
0.99

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.565

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

p-Fluorophenylglycine in the urine of baboons treated with HPTP, the tetrahydropyridine analog of haloperidol.

Life Sci. 65(5) , 535-42, (1999)

We report the presence of p-fluorophenylglycine (p-FPG) in the urine of six baboons treated with HPTP, the tetrahydropyridine dehydration product of haloperidol (HP). Oxidative N-dealkylation, the maj...

4-fluorophenylglycine as a label for 19F NMR structure analysis of membrane-associated peptides.

ChemBioChem. 4(11) , 1151-63, (2003)

The non-natural amino acid 4-fluorophenylglycine (4F-Phg) was incorporated into several representative membrane-associated peptides for dual purpose. The (19)F-substituted ring is directly attached to...