2-Phenoxypropanoic acid

Names

[ CAS No. ]:
940-31-8

[ Name ]:
2-Phenoxypropanoic acid

[Synonym ]:
Propanoic acid, 2-phenoxy-
phenoxypropanoic acid
EINECS 213-370-5
DL-2-PHENOXYPROPIONIC ACID
2-phenoxy-propanoicaci
(+/-)-2-phenyloxypropanoic acid
phenoxypropionic acid
acidephenoxy-2-propionique
a-Phenoxypropionic acid
2-Phenoxypropionsure
(2RS)-2-phenoxypropionic acid
2-Phenoxy-propanoic acid
MFCD00002643
2-phenoxy-propionicaci
2-Phenoxypropanoic acid
Propionic acid,2-phenoxy

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
265.0±0.0 °C at 760 mmHg

[ Melting Point ]:
112-115 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀O₃

[ Molecular Weight ]:
166.174

[ Flash Point ]:
112.7±13.3 °C

[ Exact Mass ]:
166.062988

[ PSA ]:
46.53000

[ LogP ]:
1.69

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.530

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UF6515000

CHEMICAL NAME :: Propionic acid, 2-phenoxy-

CAS REGISTRY NUMBER :: 940-31-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H10-O3

MOLECULAR WEIGHT :: 166.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 391 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSPMA6 Travaux de la Societe de Pharmacie de Montpellier. (Soc. de Pharmacie de Montpellier, Faculte de Pharmacie de Montpellier, Ave. Ch.-Flahault, 34060 Montpellier, France) V.1- 1942- Volume(issue)/page/year: 34,121,1974

Safety Information

[ Hazard Codes ]:
Xi,C

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
UF6515000

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Separation of enantiomers on HPLC chiral stationary phases based on human plasma alpha1-acid glycoprotein: effect of sugar moiety on chiral recognition ability.

Enantiomer 5(1) , 37-45, (2000)

HPLC chiral stationary phases based on human plasma alpha1-acid glycoprotein (AGP) and partially deglycosylated AGP (pd-AGP) were prepared to investigate the effects of sugar moiety of AGP on chiral d...

Solubilization of two structurally related anticancer drugs: XK-469 and PPA.

J. Pharm. Sci. 95(1) , 97-107, (2006)

The efficiency of a solubilization technique is determined by the physical-chemical properties of the drug. This study investigates the solubilization on two structurally related anticancer drugs, XK-...

Chlorination of 2-phenoxypropanoic acid with NCP in aqueous acetic acid: using a novel ortho-para relationship and the para/meta ratio of substituent effects for mechanism elucidation.

J. Org. Chem. 72(14) , 5327-36, (2007)

Rate constants were measured for the oxidative chlorodehydrogenation of (R,S)-2-phenoxypropanoic acid and nine ortho-, ten para- and five meta-substituted derivatives using (R,S)-1-chloro-3-methyl-2,6...