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Mipicoledine

Names

[ CAS No. ]:
942149-56-6

[ Name ]:
Mipicoledine

[Synonym ]:
Carbonic acid, (3β)-cholest-5-en-3-yl 3,5-dichloro-2-methoxy-6-(trichloromethyl)-4-pyridinyl ester
(3β)-Cholest-5-en-3-yl 3,5-dichloro-2-methoxy-6-(trichloromethyl)-4-pyridinyl carbonate

Biological Activity

[Description]:

Mipicoledine is a potential neuro-alkylating agent for study of glioblastoma and metastatic cancers involving the central nervous system[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker
Research Areas >> Neurological Disease

[References]

[1]. Lee Roy Morgan,et, al. Carbonate and carbamate derivatives of 4-demethylpenclomedine as novel anticancer agents.Cancer Chemother Pharmacol. 2009 Sep; 64(4): 829–835.Published online 2009 Mar 3.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
689.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C35H48Cl5NO4

[ Molecular Weight ]:
724.02

[ Flash Point ]:
370.6±31.5 °C

[ Exact Mass ]:
721.202576

[ LogP ]:
14.34

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.569

Related Compounds