9-Aminophenanthrene

Names

[ CAS No. ]:
947-73-9

[ Name ]:
9-Aminophenanthrene

[Synonym ]:
EINECS 213-431-6
Phenanthren-9-ylaMine
9-aminophenantrene
9-Phenanthrylamine
9-PHENANTHRENAMINE
2-aminophenanthrene
9-AMINOPHENANTHRENE
Phenanthrylamine
MFCD00001177

Chemical & Physical Properties

[ Density]:
1.208g/cm3

[ Boiling Point ]:
408.2ºC at 760mmHg

[ Melting Point ]:
137-139ºC(lit.)

[ Molecular Formula ]:
C₁₄H₁₁N

[ Molecular Weight ]:
193.24400

[ Flash Point ]:
224.4ºC

[ Exact Mass ]:
193.08900

[ PSA ]:
26.02000

[ LogP ]:
4.15640

[ Index of Refraction ]:
1.765

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG0175000

CHEMICAL NAME :: 9-Phenanthrylamine

CAS REGISTRY NUMBER :: 947-73-9

BEILSTEIN REFERENCE NO. :: 2209422

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H11-N

MOLECULAR WEIGHT :: 193.26

WISWESSER LINE NOTATION :: L B666J HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 450 mg/kg/6D-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 250 ng/plate

REFERENCE :: JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,293,1983

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26;S37/S39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
SG0175000

[ HS Code ]:
2921499090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

"Allosterism" in the elementary steps of the cytochrome P450 reaction cycle.

Drug Metab. Rev. 36(2) , 219-30, (2004)

Cytochrome P450-dependent drug metabolism in vitro frequently deviates from simple Michaelis-Menten kinetic models, and demonstrates both positive and negative homotropic and heterotropic effects. The...

Fluorometric high-performance liquid chromatography of 9-aminophenanthrene-derivatized free fatty acids.

J. Chromatogr. A. 305(2) , 261-70, (1984)

The application of 9-aminophenanthrene (9-AP), a fluorescence-labeling reagent for free fatty acids (FFA), was examined. 9-AP dissolved in benzene was added to a benzene solution of FFA chlorides deri...

HPLC on Chiralcel OJ-R for enantiomer separation and analysis of ketoprofen, from horse plasma, as the 9-aminophenanthrene derivative.

J. Pharm. Pharmacol. 50(3) , 291-6, (1998)

Racemic ketoprofen is a non-steroidal anti-inflammatory drug used to treat musculoskeletal and colic conditions in horses. The enantioselective chiral inversion of ketoprofen administered to horses ha...