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5-Chloro-2-methylaniline

Names

[ CAS No. ]:
95-79-4

[ Name ]:
5-Chloro-2-methylaniline

[Synonym ]:
5-Chloro-2-toluidine
2-METHYL-5-CHLOROANILINE
ansibaseredkb
5-CHLORO-O-TOLUIDINE (NH2=1)
5-Chloro-o-toluidine
5-CHLORO-2-METHYLANILINE D
5-Chloro-2-methylaniline
lakeredbkbase
4-chloro-2-amino-toluene
2-AMINO-4-CHLOROTOLUENE 95-79-4
5-CHLORO-2-METHYLANILINE FOR SYNTHESIS
4-CHLORO-2-AMINOTOLUENE
MFCD00007779
1-amino-2-methyl-5-chlorobenzene
BENZENAMINE,5-CHLORO-2-METHYL-
RED KB BASE
fastredkbssalt
2-AMINO-4-CHLUOROTOLUENE
EINECS 202-452-6
ZR CG F1
5-CHLORO-2-METHYLANILINE (2-AMINO-4-CHLOROTOLUENE)
Benzenamine, 5-chloro-2-methyl-
5-CHLORO-0-TOLUIDINE
fastredkbamine
5-CHLOR-2-METHYLANILIN
2-amino-4-chlorotoluene
PCOT
2-AMINO-4-CHLOROMETHYLBENZENE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
237.0±0.0 °C at 760 mmHg

[ Melting Point ]:
22 °C

[ Molecular Formula ]:
C7H8ClN

[ Molecular Weight ]:
141.598

[ Flash Point ]:
160.0±0.0 °C

[ Exact Mass ]:
141.034531

[ PSA ]:
26.02000

[ LogP ]:
2.27

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Water Solubility ]:
< 1 g/L (22 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU5075000
CHEMICAL NAME :
o-Toluidine, 5-chloro-
CAS REGISTRY NUMBER :
95-79-4
BEILSTEIN REFERENCE NO. :
0878504
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C7-H8-Cl-N
MOLECULAR WEIGHT :
141.61
WISWESSER LINE NOTATION :
ZR CG F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
464 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
164 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - adrenal cortex tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
131 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
262 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
TYPE OF TEST :
Mutation test systems - not otherwise specified

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993

Safety Information

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38;R40

[ Safety Phrases ]:
S26-S45-S36/37/39

[ RIDADR ]:
UN 3429 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
XU5075000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29214300

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2921430090

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%


Related Compounds