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AZD-9819

Names

[ CAS No. ]:
956907-23-6

[ Name ]:
AZD-9819

[Synonym ]:
6-[1-(4-Cyanophenyl)-1H-pyrazol-5-yl]-N-ethyl-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydro-2-pyrazinecarboxamide
Azd-9819
2-Pyrazinecarboxamide, 6-[1-(4-cyanophenyl)-1H-pyrazol-5-yl]-N-ethyl-3,4-dihydro-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-

Biological Activity

[Description]:

AZD-9819 is an inhibitor of human neutrophil elastase for potential treatment of chronic obstructive pulmonary disease. COPD Phase 1 Discontinued

[References]

References 1. Gu C, et al. Drug Metab Dispos. 2015 Oct;43(10):1441-9. View Related Products by Target Elastase COPD

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C25H19F3N6O2

[ Molecular Weight ]:
492.453

[ Exact Mass ]:
492.152161

[ LogP ]:
3.41

[ Index of Refraction ]:
1.630

Related Compounds