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TRIBROMOHYDRIN

Names

[ CAS No. ]:
96-11-7

[ Name ]:
TRIBROMOHYDRIN

[Synonym ]:
Glycerol tribromohydrin
1,2,3-tribrompropane
Propane,1,2,3-tribromo
1,2,3-Tribromopropane
sym-Tribromopropane
1,2,3-tribromo propane
MFCD00017884
Glyceryl tribromohydrin
TRIBROMOHYDRIN
Allyl Tribromide
EINECS 202-478-8
tribromo-1,2,3 propane
glyceroltribromhydrine
s-Tribromopropane
1,2,3-Tribrom-propan
Propane, 1,2,3-tribromo-

Chemical & Physical Properties

[ Density]:
2.4±0.1 g/cm3

[ Boiling Point ]:
220.5±8.0 °C at 760 mmHg

[ Melting Point ]:
16-17 °C(lit.)

[ Molecular Formula ]:
C3H5Br3

[ Molecular Weight ]:
280.784

[ Flash Point ]:
87.7±13.2 °C

[ Exact Mass ]:
277.794128

[ LogP ]:
3.31

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.577

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ8300000
CHEMICAL NAME :
Propane, 1,2,3-tribromo-
CAS REGISTRY NUMBER :
96-11-7
BEILSTEIN REFERENCE NO. :
1732082
LAST UPDATED :
199701
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C3-H5-Br3
MOLECULAR WEIGHT :
280.81
WISWESSER LINE NOTATION :
E1YE1E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
250 mg/kg
SEX/DURATION :
male 5 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
23869 ug/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male Reproductive - Specific Developmental Abnormalities - urogenital system
TYPE OF TEST :
DNA damage

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
250 mg/kg/5D (Continuous)
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 101,321,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1864 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 176 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335-H351

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38;R68

[ Safety Phrases ]:
S26-S27-S36/37/39

[ RIDADR ]:
2810

[ WGK Germany ]:
3

[ RTECS ]:
TZ8300000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2903399090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2903399090

[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Mutagenicity of halogenated propanes and their methylated derivatives.

Environ. Mol. Mutagen. 12(2) , 253-9, (1988)

1,2,3-Tribromopropane, 1,2,3-trichloropropane, and 1,2-dibromo-3-chloropropane are mutagenic in strains TA1535 and TA100 of Salmonella typhimurium, but only in the presence of rat liver S9 mix. This r...


More Articles


Related Compounds