p-nitrophenacyl bromide
Names
[ CAS No. ]:
99-81-0
[ Name ]:
p-nitrophenacyl bromide
[Synonym ]:
p-Nitro-α-bromoacetophenone
Ethanone, 2-bromo-1- (4-nitrophenyl)-
EINECS 202-789-9
2-Bromo-1-(4-nitrophenyl)ethanone
α-Bromo-4-nitroacetophenone
Ethanone, 2-bromo-1-(4-nitrophenyl)-
p-nitrophenacyl bromide
4'-Nitro-2-bromoacetophenone
α-Bromo-p-nitroacetophenone
2-Bromo-4'-nitroacentophenone
Acetophenone, 2-bromo-4'-nitro-
2-Bromo-1-(4-nitrophenyl)ethan-1-one
MFCD00007356
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
325.2±17.0 °C at 760 mmHg
[ Melting Point ]:
94-99 °C(lit.)
[ Molecular Formula ]:
C8H6BrNO3
[ Molecular Weight ]:
244.042
[ Flash Point ]:
150.5±20.9 °C
[ Exact Mass ]:
242.953094
[ PSA ]:
62.89000
[ LogP ]:
1.95
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.609
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3261 8/PG 2
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2914700090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
Eur. J. Pharm. Sci. 78 , 190-7, (2015)
A set of 4-arylthiazolylhydrazones derived from 1-indanones (TZHs) previously synthesized and assayed against Trypanosoma cruzi, the causative agent of Chagas disease, were explored in terms of confor...
Active site of bee venom phospholipase A2: the role of histidine-34, aspartate-64 and tyrosine-87.Biochemistry 35(14) , 4591-601, (1996)
In bee venom phospholipase A2, histidine-34 probably functions as a Brønsted base to deprotonate the attacking water. Aspartate-64 and tyrosine-87 form a hydrogen bonding network with histidine-34. We...
Chemical modification and inactivation of rat liver microsomal cytochrome P-450c by 2-bromo-4'-nitroacetophenone.J. Biol. Chem. 261(25) , 11478-86, (1986)
The alkylating agent 2-bromo-4'-nitroacetophenone (BrNAP) binds covalently to each of 10 isozymes of purified rat liver microsomal cytochrome P-450 (P-450a-P-450j) but substantially inhibits the catal...