Methoxypolyethylene glycol maleimide

Names

[ Name ]:
Methoxypolyethylene glycol maleimide

[Synonym ]:
Poly(oxy-1,2-ethanediyl), α-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]-ω-methoxy-

Biological Activity

[Description]:

Methoxypolyethylene glycol maleimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Melting Point ]:
48-52 °C

[ Molecular Formula ]:
C₉H₁₃NO₄

[ Molecular Weight ]:
199.20400

[ Flash Point ]:
>110 °C

[ Exact Mass ]:
199.08400

[ PSA ]:
55.84000

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
39072090

Articles

Studies of bioactivity, conformation and pharmacokinetic profiles of site-specific PEGylated thymosin alpha 1 derivatives.

Drug Metab. Lett. 1 , 232-240, (2007)

Site-specific mono-PEGylations were performed in different conformational regions of Thymosin alpha 1 (T alpha 1) by introducing one cysteine residue into the chosen site and coupling with thiol-speci...

Site-directed pegylation of recombinant interleukin-2 at its glycosylation site.

Biotechnology 8 , 343-346, (1990)

We have modified recombinant interleukin-2 (rIL-2) to facilitate site-directed covalent attachment of monomethoxy polyethylene glycol (PEG). The site chosen for modification and subsequent covalent at...

Analysis of functionalization of methoxy-PEG as maleimide-PEG.

Anal. Biochem. 374 , 231-242, (2008)

The design of the extension arm-facilitated PEGylation (EAFP) of proteins takes advantage of the high selective and quantitative aspects of the thiol-maleimide reaction. However, the efficiency of EAF...