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Kadsurin A

Names

[ CAS No. ]:
99340-07-5

[ Name ]:
Kadsurin A

[Synonym ]:
(2S,3R,3aS,7aR)-5-Allyl-2-(1,3-benzodioxol-5-yl)-3a,7a-dimethoxy-3-methyl-3,3a,7,7a-tetrahydro-1-benzofuran-6(2H)-one
6(2H)-Benzofuranone, 2-(1,3-benzodioxol-5-yl)-3,3a,7,7a-tetrahydro-3a,7a-dimethoxy-3-methyl-5-(2-propen-1-yl)-, (2S,3R,3aS,7aR)-
(2S,3R,3aS,7aR)-2-(1,3-benzodioxol-5-yl)-3a,7a-dimethoxy-3-methyl-5-(prop-2-en-1-yl)-3,3a,7,7a-tetrahydro-1-benzofuran-6(2H)-one

Biological Activity

[Description]:

Kadsurin A is a new lignan can be isolated from Piper futokadsura. Kadsurin A is a platelet activating factor (PAF) receptor antagonist that weakly inhibits the binding of PAF to its receptor[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[References]

[1]. Chang M N, et al. Neolignans from Piper futokadsura[J]. Phytochemistry, 1985, 24(9): 2079-2082.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
487.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H24O6

[ Molecular Weight ]:
372.41

[ Flash Point ]:
212.4±28.8 °C

[ Exact Mass ]:
372.157288

[ PSA ]:
63.22000

[ LogP ]:
3.72

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.578

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds