2-[1H-indol-3-yl(phenyl)methyl]-1-azabicyclo[2.2.2]octan-3-one,hydrochloride
Names
[ CAS No. ]:
102338-84-1
[ Name ]:
2-[1H-indol-3-yl(phenyl)methyl]-1-azabicyclo[2.2.2]octan-3-one,hydrochloride
[Synonym ]:
4-<(3'-Indolyl)benzyl>-3-hydroxyquinuclidine hydrochloride
Chemical & Physical Properties
[ Molecular Formula ]:
C22H23ClN2O
[ Molecular Weight ]:
366.88400
[ Exact Mass ]:
366.15000
[ PSA ]:
36.10000
[ LogP ]:
4.70300
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VD7186000
- CHEMICAL NAME :
- 3-Quinuclidinone, 2-(alpha-(3-indolyl)benzyl)-, monohydrochloride
- CAS REGISTRY NUMBER :
- 102338-84-1
- LAST UPDATED :
- 198609
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H22-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 366.92
- WISWESSER LINE NOTATION :
- T66 A B AV CNTJ BYR&- DT56 BMJ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - muscle contraction or spasticity Skin and Appendages - hair
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,345,1981