N-butyl-4-methoxy-7,7-dimethyl-6,8-dihydropyrimido[4,5-b][1,4]benzothiazin-9-amine,hydrobromide
Names
[ CAS No. ]:
102688-85-7
[ Name ]:
N-butyl-4-methoxy-7,7-dimethyl-6,8-dihydropyrimido[4,5-b][1,4]benzothiazin-9-amine,hydrobromide
[Synonym ]:
N-butyl-4-methoxy-7,7-dimethyl-6,8-dihydropyrimido[4,5-b][1,4]benzothiazin-9-amine
4-Methoxy-7,7-dimethyl-9-butylamino-7,8-dihydro-1,3-diazaphenothiazine hydrobromide
6H-Pyrimido(4,5-b)(1,4)benzothiazin-9-amine,7,8-dihydro-N-butyl-7,7-dimethyl-4-methoxy-,monohydrobromide
7,8-Dihydro-N-butyl-7,7-dimethyl-4-methoxy-6H-pyrimido(4,5-b)(1,4)benzothiazin-9-amine HBr
Chemical & Physical Properties
[ Molecular Formula ]:
C17H25BrN4OS
[ Molecular Weight ]:
413.37600
[ Exact Mass ]:
412.09300
[ PSA ]:
84.70000
[ LogP ]:
4.86930
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UW7681515
- CHEMICAL NAME :
- 6H-Pyrimido(4,5-b)(1,4)benzothiazin-9-amine, 7,8-dihydro-N-butyl-7,7-dimethyl-4-methoxy-, monohydrobromide
- CAS REGISTRY NUMBER :
- 102688-85-7
- LAST UPDATED :
- 198906
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H24-N4-O-S.Br-H
- MOLECULAR WEIGHT :
- 413.43
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 255 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,459,1985