[(11Z,13E)-6-[5-(5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[5-(dimethylamino)-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate

Names

[ Name ]:
[(11Z,13E)-6-[5-(5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[5-(dimethylamino)-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate

[Synonym ]:
4'-O-Acetylspiramycin C
4'-Acetylspiramycin III
Leucomycin V,9-O-(5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)-,4(sup B)-acetate 3-propanoate,(9-(2R,5S,6R))

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
931.9ºC at 760mmHg

[ Molecular Formula ]:
C₄₈H₈₀N₂O₁₆

[ Molecular Weight ]:
941.15300

[ Flash Point ]:
517.4ºC

[ Exact Mass ]:
940.55100

[ PSA ]:
207.52000

[ LogP ]:
3.85680

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.536

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OH4730560

CHEMICAL NAME :: Leucomycin V, 9-O-(5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2- yl)-, 4(sup B)-acetate 3- propanoate, (9-(2R,5S,6R))-

CAS REGISTRY NUMBER :: 112501-15-2

LAST UPDATED :: 199303

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C48-H80-N2-O16

MOLECULAR WEIGHT :: 941.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 949 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 43,1521,1990