Quinoline-2-carboxylic acid-d6

Names

[ CAS No. ]:
1219802-18-2

[ Name ]:
Quinoline-2-carboxylic acid-d6

[Synonym ]:
Quinaldic acid
2-Quinaldic acid
Quinolin-2-carboxylic acid
2-Quinolinecarboxylic acid
Quinoline-2-carboxylic acid

Biological Activity

[Description]:

Quinoline-2-carboxylic acid-d6 is the deuterium labeled Quinoline-2-carboxylic acid[1]. Quinoline-2-carboxylic acid is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
348.7±17.0 °C at 760 mmHg

[ Molecular Formula ]:
C10HD6NO2

[ Molecular Weight ]:
179.20500

[ Flash Point ]:
164.7±20.9 °C

[ Exact Mass ]:
179.08500

[ PSA ]:
50.19000

[ LogP ]:
2.17

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.685

Related Compounds