Nefopam D3

Names

[ CAS No. ]:
1346747-15-6

[ Name ]:
Nefopam D3

Biological Activity

[Description]:

Nefopam D3 (Fenazoxine D3) is a deuterium labeled Nefopam (Fenazoxine). Nefopam is a centrally-acting but non-opioid analgesic drug, and Nefopam targets β-catenin protein level in mesenchymal cells[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Kim KH, et al. Rediscovery of nefopam for the treatment of neuropathic pain. Korean J Pain. 2014 Apr;27(2):103-11.

[2]. Baht GS, et al. Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. Bone. 2017 May;98:31-36.

[3]. Poon R, et al. A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. PLoS One. 2012;7(5):e37940.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H16D3NO

[ Molecular Weight ]:
256.36

Related Compounds