Patulin-13C7

Names

[ Name ]:
Patulin-13C7

[Synonym ]:
MFCD17018964
Patulin-13C7 solution
4H-Furo[3,2-c]pyran-2(6H)-one-2,3,3a,4,6,7,7a-13C7, 4-hydroxy-
4-Hydroxy(13C7)-4H-furo[3,2-c]pyran-2(6H)-one
4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one-13C7
Patulin-13C7
EINECS 200-835-2

Biological Activity

[Description]:

Patulin-13C7 (Terinin-13C7) is the 13C labeled Patulin (HY-N6779)[1]. Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage[2][3][4][5].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
₁₃C₇H₆O₄

[ Molecular Weight ]:
161.07

[ Exact Mass ]:
161.050095

[ Index of Refraction ]:
1.603

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
F+