diethyl-[2-(4-methylanilino)-2-oxoethyl]azanium,chloride
Names
[ CAS No. ]:
13995-54-5
[ Name ]:
diethyl-[2-(4-methylanilino)-2-oxoethyl]azanium,chloride
[Synonym ]:
IEM-218
2-(Diethylamino)-4'-methylacetanilide monohydrochloride
p-ACETOTOLUIDIDE,2-(DIETHYLAMINO)-,HYDROCHLORIDE
Acetamide,2-(diethylamino)-N-(4-methylphenyl)-,monohydrochloride
2-(Diethylamino)-p-acetotoluidide hydrochloride
N,N-Diaethyl-glycin-p-toluidid,Hydrochlorid
N,N-diethyl-glycine p-toluidide,hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
364.5ºC at 760 mmHg
[ Molecular Formula ]:
C13H21ClN2O
[ Molecular Weight ]:
256.77200
[ Flash Point ]:
174.3ºC
[ Exact Mass ]:
256.13400
[ PSA ]:
32.34000
[ LogP ]:
3.15030
[ Vapour Pressure ]:
1.67E-05mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AN3457000
- CHEMICAL NAME :
- p-Acetotoluidide, 2-(diethylamino)-, hydrochloride
- CAS REGISTRY NUMBER :
- 13995-54-5
- LAST UPDATED :
- 199309
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C13-H20-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 256.81
- WISWESSER LINE NOTATION :
- 2N2&1VMR D1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 21,144,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 24,539,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 81 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,629,1991