Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

Names

[ CAS No. ]:
1638970-46-3

[ Name ]:
Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

Biological Activity

[Description]:

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vivo]

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) (26.2 micro-rubbing/kg, IV, weekly for 4 weeks) suppresses tumor growth in mice bearing Panc-1 tumor[1].

[References]

[1]. Liu Chen, et al. Tumor microenvironment specific activated micromolecular targeted conjugate and application thereof. CN104147612A.

Chemical & Physical Properties

[ Molecular Formula ]:
C67H101N11O16

[ Molecular Weight ]:
1316.58

Related Compounds