HBV-IN-31

Names

[ CAS No. ]:
2413192-95-5

[ Name ]:
HBV-IN-31

Biological Activity

[Description]:

HBV-IN-31 is a potent cccDNA (covalently closed circular DNA) inhibitor. HBV-IN-31 shows anti-HBV activity with an IC50 value of 0.13 µM for HBsAg. HBV-IN-31 inhibits cell growth[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> HBV

[In Vitro]

HBV-IN-31 (example 46) (0-50 µM; 5 days) 在 HepDES19 细胞中抑制细胞生长，IC50 为 16.01 µM[1]。 Cell Viability Assay[1] Cell Line: HepDESl9 cells Concentration: 0-50 µM Incubation Time: 5 days Result: Inhibited cell viability with an IC50 of 16.01 µM.

[References]

[1]. Song Feng, et al. Flavone compounds for the treatment and prophylaxis of hepatitis b virus disease. WO2020053249A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H18ClNO6

[ Molecular Weight ]:
439.85

Related Compounds