HBV-IN-32

Names

[ CAS No. ]:
2413193-04-9

[ Name ]:
HBV-IN-32

Biological Activity

[Description]:

HBV-IN-32 is a potent cccDNA (covalently closed circular DNA) inhibitor. HBV-IN-32 shows anti-HBV activity with an IC50 value of 0.14 µM for HBsAg. HBV-IN-32 inhibits cell growth[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> HBV

[In Vitro]

HBV-IN-31 (example 57) (0-50 µM; 5 days) 在 HepDES19 细胞中抑制细胞生长，IC50 为 0.09 µM[1]。 Cell Viability Assay[1] Cell Line: HepDESl9 cells Concentration: 0-50 µM Incubation Time: 5 days Result: Inhibited cell viability with an IC50 of 0.09 µM.

[References]

[1]. Song Feng, et al. Flavone compounds for the treatment and prophylaxis of hepatitis b virus disease. WO2020053249A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H19ClO5S

[ Molecular Weight ]:
430.90

Related Compounds