Isoleucyl tRNA synthetase-IN-1

Names

[ CAS No. ]:
2502167-19-1

[ Name ]:
Isoleucyl tRNA synthetase-IN-1

Biological Activity

[Description]:

Isoleucyl tRNA synthetase-IN-1 (compound 11) is a potent and selective isoleucyl-tRNA synthetase (IleRS) inhibitor, with a Ki,app of 88 nM[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. De Ruysscher D, et al. Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase. Bioorg Med Chem. 2020 Aug 1;28(15):115580.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H35N5O7S

[ Molecular Weight ]:
525.62

Related Compounds