Sulindac sulfide-d3
Names
[ CAS No. ]:
250608-66-3
[ Name ]:
Sulindac sulfide-d3
Biological Activity
[Description]:
Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
[Related Catalog]:
[In Vitro]
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C20H14D3FO2S
[ Molecular Weight ]:
343.43