ALK5-IN-27

Names

[ CAS No. ]:
2785430-83-1

[ Name ]:
ALK5-IN-27

Biological Activity

[Description]:

ALK5-IN-27 (Compound EX-04) is a potent ALK-5 inhibitor with an IC50 ≤10 nM. ALK5-IN-27 also inhibits ALK-2 (selectivity ALK2/ALK5 ≤10)[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

ALK5:≤10 nM (IC50)

ALK2


[References]

[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H28N8

[ Molecular Weight ]:
440.54

Related Compounds