(6S,8R,9S,10R,13S,14S,17S)-6,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Names

[ CAS No. ]:
2944-87-8

[ Name ]:
(6S,8R,9S,10R,13S,14S,17S)-6,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

[Synonym ]:
6alpha-Hydroxytestosterone
6-hydroxytestosterone
4-androstene-6alpha,17beta-diol-3-one
Androst-4-ene-6|A,17|A-diol-3-one
4-Androstene-6|A,17|A-diol-3-one
6|A-Hydroxytestosterone

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
479.8ºC at 760 mmHg

[ Molecular Formula ]:
C19H28O3

[ Molecular Weight ]:
304.42400

[ Flash Point ]:
258.1ºC

[ Exact Mass ]:
304.20400

[ PSA ]:
57.53000

[ LogP ]:
2.85000

[ Vapour Pressure ]:
3.19E-11mmHg at 25°C

[ Index of Refraction ]:
1.578

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332-H351-H361

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22;R40;R63

[ Safety Phrases ]:
S22-S36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

DownStream

Articles

Testosterone-metabolizing capacity and characteristics of adrenal microsomes in human fetus in vitro.

J. Pediatr. Endocrinol. Metab. 23(1-2) , 143-52, (2010)

We describe the metabolite spectrum of testosterone (T) in human fetal adrenal in vitro, and verify possible roles of CYP3A and 2C isoforms of human fetal adrenal in T metabolism which respond to T me...

The hepatic and intestinal metabolic activities of P450 in rats with surgery- and drug-induced renal dysfunction.

Pharm. Res. 20(10) , 1591-4, (2003)

The hepatic and intestinal metabolic activities of P450 were evaluated in rats with surgery- and drug-induced renal dysfunction.Renal failure was induced by five-sixths nephrectomy (NR), bilateral ure...

The use of heat treatment to eliminate drug interactions due to grapefruit juice.

Biol. Pharm. Bull. 29(11) , 2274-8, (2006)

Grapefruit juice (GJ) contains components that may increase the bioavailability of drugs; however, approaches to the removal of these components have been little investigated. It is known that furanoc...


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Related Compounds